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Follicular thyroid cancer accounts for 15% of thyroid cancer and occurs more commonly in women over 50 years of age. Thyroglobulin (Tg) can be used as a tumor marker for well-differentiated follicular thyroid cancer. Follicular cells are the thyroid cells responsible for the production and secretion of thyroid hormones. ==Classification== It is impossible to distinguish between follicular adenoma and carcinoma on cytological grounds. If fine needle aspiration cytology (FNAC) suggests follicular neoplasm, thyroid lobectomy should be performed to establish the histopathological diagnosis. Features ''sine qua non'' for the diagnosis of follicular carcinoma are capsular invasion and vascular invasion by tumor cells. Still, focuses of the capsular invasion should be carefully evaluated and discriminated from the capsular rupture due to FNA penetration resulting in WHAFFT (''worrisome histologic alterations following FNA of thyroid''). * Follicular carcinoma tends to metastasize to lung and bone via the bloodstream. * Papillary thyroid carcinoma commonly metastasizes to cervical lymph nodes. HMGA2 has been proposed as a marker to identify malignant tumors. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Follicular thyroid cancer」の詳細全文を読む スポンサード リンク
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